Assessment of the Serum Levels of Creatinine, Urea and Glucose among Chronic Consumers of Agbo Herbal Medicine in Etsako West Local Government Area, Edo State

Ijeoma Evangeline Umeche, Ebuka Anthony Emekwisie, Nkiruka Chinenye Nwoka, Marian Garba Oguche

Citation: Ijeoma Evangeline Umeche, Ebuka Anthony Emekwisie, Nkiruka Chinenye Nwoka, Marian Garba Oguche, "Assessment of the Serum Levels of Creatinine, Urea and Glucose among Chronic Consumers of Agbo Herbal Medicine in Etsako West Local Government Area, Edo State", Universal Library of Biological Sciences, Volume 01, Issue 01.

Copyright: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study investigated the serum levels of creatinine, urea, and glucose in chronic consumers of agbo herbal medicine in Etsako West Local Government Area, Edo State, Nigeria. A total of 181 participants, both male and female, were recruited and divided into two groups: a test group comprising chronic agbo consumers and a control group of non-consumers. Blood samples were collected intravenously and processed to obtain plasma for analysis. Serum creatinine, urea, and glucose levels were measured using the Randox reagent kit. The results revealed significantly elevated serum levels of creatinine (1.117 ± 0.5608 vs. 0.593 ± 0.3236 mg/dL), urea (58.66 ± 10.640 vs. 42.17 ± 13.244 mg/dL), and glucose (138.30 ± 84.467 vs. 113.03 ± 27.635 mg/dL) in the test group compared to the control group (p < 0.05). Independent t-tests confirmed significant differences between the groups for creatinine, urea, and glucose levels. Further analysis showed that daily consumers within the test group exhibited significantly higher glucose levels compared to the control group (mean difference = 75.749; p < 0.05).These findings suggest that chronic consumption of agbo herbal medicine may adversely affect kidney function and glucose regulation. While the data indicates a replicable impact of agbo on these parameters, further research with larger sample sizes is necessary to clarify the relationship and establish safe consumption guidelines. Until then, a reduced intake of agbo is recommended to mitigate potential health risks.


Keywords: Agbo, Herbal Medicine, Nephrotoxic, Glucose.

Download doi https://doi.org/10.70315/uloap.ulbsc.2024.0101002