Does Preoperative Anemia Influences Postoperative Mortality After Isolated CABG? A Sequential Analysis

Thierry CAUS, Toufik IAICHE

Citation: Thierry CAUS, Toufik IAICHE, "Does Preoperative Anemia Influences Postoperative Mortality After Isolated CABG? A Sequential Analysis", Universal Library of Medical and Health Sciences, Volume 02, Issue 02.

Copyright: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The potential impact of preoperative anemia on postoperative mortality after CABG is becoming widely endorsed by best practice guidelines in patient blood management. However clinical evidences are still scarce and very large number of patients are needed to prove certainty in preemptive therapeutic measures like iron substitution. We aimed at illustrate the usefulness of CUSUM in this setting and reviewed a historical series of 1282 patients operated on for isolated CABG. The negative effect of preoperative anemia on fatal outcome after CABG could be assessed with an unacceptable rate of failure after 266 anemic patients only. This should encourage trials based on sequential analysis with the hope to fasten emergence of conclusive results.


Keywords: Coronary surgery, Control Charts, Cusum, Anemia, Outcomes.

Download doi https://doi.org/10.70315/uloap.ulmhs.2024.0202005