Photobiomodulation in Combination with Biomimetic Serums: An Innovative Protocol for Skin Restoration in Patients with Post-Acne

Citation: Anastasiia Haraieva, "Photobiomodulation in Combination with Biomimetic Serums: An Innovative Protocol for Skin Restoration in Patients with Post-Acne", Universal Library of Medical and Health Sciences, Volume 02, Issue 02.

Copyright: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Post-acne, including atrophic scars, post-inflammatory erythema (PIE), and post-inflammatory hyperpigmentation (PIH), represents not only a dermatological but also a pronounced psychosocial problem, affecting, according to clinical observations, up to 95 % of patients who have experienced acne. Traditionally applied more aggressive correction methods (ablative laser resurfacing, medium–deep chemical peels, etc.) are associated with a high incidence of adverse events and a prolonged recovery period. This is particularly critical in individuals with sensitive skin and dark phototypes (Fitzpatrick IV–VI), who, being more predisposed to the development of PIH, paradoxically at the same time belong to a high-risk group for complications with aggressive interventions. Under these conditions, the aim of the study is the theoretical substantiation of a minimally invasive synergistic protocol based on the combination of photobiomodulation (PBM) and topical application of biomimetic serums. Methodologically, the work is structured as a systematic review of publications from 2019–2024 in the PubMed and Scopus databases, with an emphasis on the analysis of cellular and molecular mechanisms of PBM and regenerative cosmeceuticals. The conclusions formulated on the basis of this analysis indicate that the combined protocol (for example, the sequence superficial peel, serum application, PBM) has a theoretical advantage over any form of monotherapy. Such a combination makes it possible simultaneously to increase the energetic potential of cells and to set a regenerative program for them, which opens up prospects for a safer and more effective reconstruction of the skin in post-acne. The presented propositions have practical significance for dermatologists, clinical estheticians, and researchers focused on the development of non-aggressive, physiological protocols of regenerative cosmetology.

Keywords: Post-Acne, Atrophic Scars, Photobiomodulation, LED Therapy, Biomimetic Peptides, Growth Factors, Post-Inflammatory Erythema, Post-Inflammatory Hyperpigmentation, Cytochrome C Oxidase, Synergistic Protocol.

https://doi.org/10.70315/uloap.ulmhs.2024.0202009