Comparison of Sonographic and Histological Findings among Women with Breast Masses in Owo

Dr. C. Adebiyi, Dr. B.O Omolase, Dr. U.O Kalu, Dr. C.E Okerek, Dr. P.O Ologunagba, Dr. C.O Omolase

Citation: Dr. C. Adebiyi, Dr. B.O Omolase, Dr. U.O Kalu, Dr. C.E Okerek, Dr. P.O Ologunagba, Dr. C.O Omolase, "Comparison of Sonographic and Histological Findings among Women with Breast Masses in Owo", Universal Library of Medical and Health Sciences, Volume 03, Issue 02.

Copyright: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This retrospective study compared the sonographic features with histopathological findings in women with breast lesions at Federal medical centre Owo, to determine the sensitivity, specificity and accuracy of ultrasound in the diagnosis of breast masses using histopathology as gold standard. Ethical approval was obtained from the Health and Research Ethics Committee of Federal Medical Centre, Owo. Sonographic reports conducted on 123 patients aged 15 to 69years (mean age 38.57years) who presented with breast lesions at Federal medical centre, Owo were retrieved from the case notes. Histopathology reports of the patients were also retrieved and correlated with the ultrasonographic findings. American College of Radiology’s Breast imaging Reporting and Data System (BI-RADS) descriptors were used to categorize the sonographic features into different BI-RADS assessment category. The BI-RADS in this study accurately predicted 63 benign breast lesions and 60 malignant lesions. Histopathology identified 65 benign breast lesions and 58 malignant lesions. The difference may be attributed to the limitation of relying purely on morphological appearances. Ultrasound BI-RADS assessment from this study has sensitivity of 96.5%, specificity of 93.8%, positive predictive value (PPV) of 93.3%, negative predictive value (NPV) of 96.8% and accuracy of 95.1%. When histopathology results were compared with that of BI-RADS predictions in this study, no statistically significant difference (p > 0.05) was observed.


Keywords: Women Breast Histology Ultrasound.

Download doi https://doi.org/10.70315/uloap.ulmhs.2025.0302007